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G-Netix
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ISM Interactive

G-Netix is a simulation game available for the Mac and PC.

Immune Attack
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Federation of American Scientists (FAS)

This free, downloadable game teaches about the immune system and is targeted to high school and college students.

Killer Flu
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Persuasive Games

In the free, online game Killer Flu, players are taught about seasonal and pandemic flu and how those differ from the influenza virus.

Pamoja Mtaani - AIDS prevention game
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Virtual Heroes

Pamoja Mtaani (Together in the Hood) is a multi-player game intended to alter the attitudes, behaviors, and risk perceptions around HIV.

Quarantine
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Institute for the Future (IFTF)
In the free, online game Quarantine, players enter the future during a time in which human societies have been threatened by an outbreak of an infectious respiratory disease. The goal is to consider all implications of the virus and respond to it bef...
Sneeze
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Oil Productions
Sneeze demonstrates how easily a virus can be transmitted from person to person. In each level of this free, online game, players infect a certain percentage of people with only one sneeze. After sneezing on a person, players watch as that sneeze get...
Supershagland
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Supershagland is an adventure game created for World's AIDS Day that seeks to educate and raise awareness about the HIV/AIDS virus. The game emphasizes the importance of condom use and other safe ways to avoid contracting the disease. Players navigat...
The Great Flu
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Ranj Serious Games

“In an effort to further raise awareness, Dutch researchers have created a game that challenges players to control a new pandemic.